Does Lipitor damage your liver?
Clinical studies revealed Lipitor can damage liver function, and the FDA has received rare post-marketing reports of both fatal and nonfatal liver failure. Other reported liver problems include jaundice, hepatitis, chronic liver damage and fatty changes to the liver.
Can statins affect liver function?
Statins should not be taken if you have severe liver disease or if blood tests suggest that your liver may not be working properly. This is because statins can affect your liver, and this is more likely to cause serious problems if you already have a severely damaged liver.
How often do statins cause liver damage?
The risk of hepatic injury caused by statins is estimated to be about 1 percent, similar to that of patients taking a placebo. Patients with transaminase levels no more than three times the upper limit of normal can continue taking statins; often the elevations will resolve spontaneously.
Does Lipitor cause high liver enzymes?
This statin side effect is dose-dependent, which means that the higher the dose of statins you are taking, the more likely you will experience an increase in liver enzymes. There are rare reports of liver failure and hepatitis associated with statins and elevated liver enzymes.
Can Atorvastatin cause liver problems?
Atorvastatin causes elevations in transaminases greater than 3-fold the ULN in approximately 0.5% of all cases, with an absolute risk of 1.2% with high-intensity therapy. Atorvastatin is the most common cause of clinically significant liver injury among statins with a reported incidence of 1/17 000 users.Ordibe
Can statins cause cirrhosis of the liver?
A recent systematic review and meta-analysis of existing data on statin use and the risk of cirrhosis development as well as the occurrence of cirrhosis-related complications in patients with CLD showed that there is a probable association between statin use and a lower risk of hepatic decompensation and mortality, and …
What does Atorvastatin do to the liver?
Which statin is safest for liver?
Doctor’s response. Low dose statins like atorvastatin (Lipitor) are safe in patients with mild liver disease (for example, patients with fatty liver and mildly abnormal liver tests in the blood such as ALT and AST).
What can I take instead of Lipitor?
Cholesterol-Lowering Treatment Options That Aren’t Statins
- Atorvastatin (Lipitor)
- Fluvastatin (Lescol)
- Simvastatin (Zocor)
- Rosuvastatin (Crestor)
- Pravastatin (Pravachol)
- Lovastatin (Mevacor)
- Pitavastatin (Livalo)
When should I take Lipitor?
While many statins are recommended to be taken in the evening, Lipitor can be taken at any time of day. Lipitor has a half-life of about 14 hours, but continues to work for 20-30 hours due to its active metabolites.
Does Lipitor damage liver?
Among the numerous side effects to be linked to Lipitor, liver damage is among the most serious. The drug has been shown to increase enzymes in the liver, which can severely affect the organ’s ability to function properly over time. This increase in liver enzymes usually does not cause any symptoms,…
Can atorvastatin affect liver function?
Liver function: Atorvastatin may reduce liver function and can cause liver failure. This medication should not be used by people with active liver disease or by people whose liver function tests are higher than normal.
How do you treat severe rash from Lipitor?
Eliminate the causative agent. In majority of cases,the cause is a drug (including Lipitor although in rare cases.