Does Chemo work on clear cell carcinoma?
Ovarian clear cell carcinomas (OCCC) are relatively resistant to platinum-based chemotherapy with lower response rates and shorter progression-free survival compared with high-grade serous cancers.
How is ovarian clear cell carcinoma treated?
The standard surgical treatment of patients with EOC is based on hysterectomy, bilateral salpingo-oophorectomy and partial omentectomy with peritoneal sampling and lymphadenectomy, and cytoreductive surgery is added especially for advanced cases.
Can chemo shrink ovarian tumor?
If your ovarian cancer has been diagnosed at a later stage then it might not be possible to perform surgery initially. Chemotherapy will be given first to shrink as much of the ovarian cancer as possible and make any subsequent surgery safer and more effective.
What is the best treatment for clear cell carcinoma?
Targeted therapy: Targeted therapy targets the changes in cancer cells that help them grow, divide, and spread. Some targeted therapies that are used to treat clear cell renal carcinoma include cabozantinib, axitinib, sunitinib, sorafenib, and pazopanib.
Is clear cell ovarian carcinoma aggressive?
Clear cell cancers are more likely to present at an early stage, as it tends to present with a large pelvic mass, or deep vein thrombosis (blood clotting). However, they are also one of the more aggressive types of ovarian cancer and progress quickly.
Is clear cell carcinoma fatal?
Patients with clear cell renal cell carcinoma (CCRCC) tend to have a worse prognosis than patients with other histologic subtypes of RCC, with 5-year disease-specific survival rates of 50-69%, compared with 67-87% for papillary RCC and 78-87% for chRCC.
Is clear cell carcinoma curable?
RCC can often be cured if it is diagnosed and treated surgically while still confined to the kidney and the immediately surrounding tissue.
How long does chemo take to shrink a tumor?
In general, chemotherapy can take about 3 to 6 months to complete. It may take more or less time, depending on the type of chemo and the stage of your condition. It’s also broken down into cycles, which last 2 to 6 weeks each.
How serious is clear cell carcinoma?
How fast does clear cell carcinoma grow?
Clear cell carcinoma (0.86 cm/year) tended to grow faster than papillary cell carcinoma (0.28 cm/year) (P = 0.066).
How long does it take Chemo to get rid of ovarian cancer?
Epithelial ovarian cancer often shrinks or even seems to go away with chemo, but the cancer cells may eventually begin to grow again. If the first chemo seemed to work well and the cancer stayed away for at least 6 to 12 months, it can be treated with the same chemotherapy used the first time.
What kind of chemotherapy is used for ovarian cancer?
High dose chemotherapy (the exact drugs used can vary depending on what cancer center is giving the treatment) Ovarian stromal tumors are not often treated with chemotherapy, but when they are, the combination of carboplatin plus paclitaxel or PEB (cisplatin/Platinol, etoposide, and bleomycin) is used most often. Chemo drugs can cause side effects.
How is clear cell carcinoma of the ovary different?
Clear cell carcinoma of the ovary has distinct biology and clinical behavior. There are significant geographical and racial differences in the incidence of clear cell carcinoma compared with other epithelial ovarian tumors.
Are there any other types of ovarian carcinoma?
The recognition that other types of ovarian carcinoma, including high-grade serous carcinoma and endometrioid carcinoma, can contain areas with clear cell change has improved the specificity of a clear cell carcinoma diagnosis, which can now be made using a combination of morphological and immunohistochemical features ( Figure 1 ).