What is a CMV donor?
Donors are given an initial CMV screening to determine their CMV status. Donors are tested specifically for IgG and IgM antibodies. If a donor is IgG positive and IgM negative, the donor has had a past exposure to CMV but does not have an active infection.
Should I use a CMV positive donor?
Those women who have had a past infection are at very low risk of transmitting CMV infection to as fetus. They are at little to no risk from using a CMV positive donor. Women who have never been exposed to CMV however, should consider using a CMV negative sperm donor.
What is CMV status mean?
CMV status is determined based on a serologic study (a test that looks for the presence of antibodies in the blood). The initial screening test is a “total antibody test”. Anybody who has ever been infected with CMV will have a positive total antibody test.
Do I need a CMV negative donor?
Between 50 and 85 percent of American adults have been exposed to CMV, with the majority of cases occurring in childhood – these individuals will test CMV positive. If you test CMV negative, it’s essential to select CMV negative sperm donors, as CMV can transmit via bodily fluids, such as semen.
Why is CMV test ordered?
Why Is the CMV Test Ordered? Your doctor can order a CMV test to learn if you currently have an active CMV infection or have had one in the past. They can also use it to learn if treatment for an active CMV infection is working.
What is CMV negative donor?
CMV or Cytomegalovirus is a virus that is not harmful to healthy adults and is found in more than half the population. Donors who have not been exposed to the virus have CMV negative blood, which is important for patients with weakened or underdeveloped immune systems.
Can you donate blood if you have CMV?
As with other viruses, once someone has had CMV, their body retains the antibodies. CMV is generally harmless to adults, but can be fatal to babies. For this reason, babies needing transfusions as part of their medical care should only receive blood from donors who have not been exposed to CMV (CMV negative).
How is CMV diagnosis?
In adults, CMV can be diagnosed by one or more of the following methods: (1) identification of CMV inclusion bodies or CMV antigen in infected tissue by using indirect immunofluorescence microscopy, (2) detection of the virus in cell culture monolayers inoculated with infected tissue or body fluids (for example, lung.
Can a person with CMV donate blood?