What is the definition of a status epilepticus?
Status epilepticus is a neurological emergency requiring immediate evaluation and management to prevent significant morbidity or mortality. Previously, status epilepticus was defined as a seizure with a duration equal to or greater than 30 minutes or a series of seizures in which the patient does not regain normal mental status between seizures.
Are there any new medications available for status epilepticus?
Treatment is evolving as new medications become available. Three new preparations—fosphenytoin, rectal diazepam, and parenteral valproate—have implications for the management of status epilepticus.
When did the FDA approve Cerebyx for status epilepticus?
Fosphenytoin (Cerebyx) received approval for treatment of status epilepticus from the U.S. Food and Drug Administration (FDA) in 1996. Fosphenytoin is a water-soluble pro-drug of phenytoin that completely converts to phenytoin following parenteral administration.
Is it possible to have convulsive status epilepsy?
Status epilepticus is very rare, most people with epilepsy will never have it. This condition is more common in young children and elderly adults. This condition can occur as: Convulsive status epilepticus.
Who is most at risk for status epilepticus?
This condition is more common in young children and elderly adults. This condition can occur as: Convulsive status epilepticus. Status epilepticus with convulsions may be more likely to lead to long-term injury. Convulsions may involve jerking motions, grunting sounds, drooling, and rapid eye movements.
When to take rocuronium or sugammadex for status epilepticus?
Intubation with succinylcholine (if there is no contraindication to this). Caution is required, however, because ongoing status epilepticus may cause hyperkalemia after >20-30 minutes. Intubation with rocuronium, followed by reversal of rocuronium with sugammadex to obtain a neurologic examination.