Can diabetes cause lichen planus?
The prevalence reported ranges from 1.6% to 37.7% with a relative risk of 2.432. Ten studies assessed the prevalence of lichen planus among patients with diabetes mellitus which showed a prevalence of lichen planus ranging from 0.5% to 6.1% with a relative risk of 1.4.
Is lichen planus linked to other diseases?
Analysis of data obtained from a Taiwan insurance database containing approximately 12,500 lichen planus patients revealed a significant association between lichen planus and systemic lupus erythematosus, Sjögren’s syndrome (significant in females only), dermatomyositis, vitiligo, and alopecia areata.
What auto immune disease causes lichen planus?
Lichen planus (LP) is thought to be an autoimmune disorder in patients with a genetic predisposition but may be caused by drugs or be associated with disorders such as hepatitis C. LP is characterized by recurrent, pruritic papules that are polygonal, flat-topped, and violaceous and can coalesce into plaques.
Is lichen planus an autoimmune disease?
Lichen planus is a chronic, inflammatory, autoimmune disease that affects the skin, oral mucosa, genital mucosa, scalp, and nails. Lichen planus lesions are described using the six P’s (planar [flat-topped], purple, polygonal, pruritic, papules, plaques).
Is lichen sclerosus associated with diabetes?
A review of 76 patients with lichen sclerosus et atrophicus reveals a number of cases in which this disorder is associated with glucose intolerance or diabetes mellitus. The performance of an oral glucose tolerance test is therefore recommended for all patients with lichen sclerosus et atrophicus.
Does metformin cause lichen planus?
In addition, cutaneous side-effects such as leukocytoclastic vasculitis, bullous pemphigoid, psoriasiform drug eruption, lichen planus and acute alopecia have been associated with metformin use and are discussed in the article.
Is lichen planus part of lupus?
Lupus erythematosus lichen planus (LE-LP) overlap syndrome remains an uncommon diagnostic entity, combining both the histologic and clinical features of lupus erythematosus and lichen planus. A rare and challenging diagnosis, clinicopathologic correlation is essential for accurate and timely identification.
What diabetes medicines cause lichen planus?
Among the oral hypoglycemic drugs, sulfonylureas have been reported in association with lichen planus [2].
Can you die from lichen planus?
Lichen planus is usually not harmful. Most often it gets better with treatment. The condition often clears up within 18 months, but may come and go for years. If lichen planus is caused by a medicine you are taking, the rash should go away once you stop the medicine.
Lichen Planus is also linked with Hepatitis C virus infection, which has been found to be a major cause of liver diseases.
Is lichen planopilaris caused by a fungus?
The name “lichen” comes from the skin lesions of lichen planus that some patients with lichen planopilaris also have. The skin lesions are flat just like lichens that one might see walking in the forest. Lichen planopilaris is not due to a fungus. It is an autoimmune inflammatory condition that causes permanent hair loss.