What is oncocytoma of kidney?
Listen. Renal oncocytoma is a benign (noncancerous) growth of the kidney. They generally do not cause any signs or symptoms and are often discovered incidentally (by chance) while a person is undergoing diagnostic imaging for other conditions.
What does oncocytoma mean?
Medical Definition of oncocytoma : a tumor (as of the parotid gland) consisting chiefly or entirely of oncocytes.
Is a renal oncocytoma malignant?
Oncocytoma of the kidney is a benign tumor. Grossly, these tumors are well-circumscribed. Microscopically, the tumor cells show nested architecture with granular cytoplasm and round nuclei. Adequate sampling is required to exclude areas of definitive solid architecture and cytoplasmic clearing.
Should oncocytoma be removed?
Although many benign tumors do not require treatment unless they are causing unpleasant symptoms, it can be difficult to confidently differentiate a renal oncocytoma from renal cell carcinoma. Most affected people are, therefore, treated with surgery which allows for confirmation of the diagnosis.
What are the symptoms of oncocytoma?
Renal oncocytomas are often asymptomatic and are frequently discovered by chance on a CT or ultrasound of the abdomen. Possible signs and symptoms of a renal oncocytoma include blood in the urine, flank pain, and an abdominal mass.
What is Oncocytic renal neoplasm?
Oncocytoma is a term generally used to describe a neoplasm of the renal parenchyma consisting of well-differentiated cells with prominently eosinophilic granular cytoplasm. We report our experience with such tumors and with 4 cases of granular cell carcinoma (grade 2).
What is Oncocytic carcinoma?
Oncocytic carcinoma, also known as malignant oncocytoma, is a malignant carcinoma. It can occur in many organs, including the breast and the pancreas, but it occurs most frequently in the thyroid. 1. The occurrence of oncocytic carcinoma in the salivary glands has rarely been reported.
What causes Oncocytic cells?
Oncocytic change is defined as cellular enlargement characterised by an abundant eosinophilic granular cytoplasm as a result of the accumulation of altered mitochondria. This is a phenomenon of metaplasia that occurs in inflammatory disorders, such as thyroiditis, or other situations that result in cellular stress.
What is an Oncocytic cyst?
Oncocytic cysts of the larynx are rare benign, slow growing lesions that are lined predominantly or exclusively by oncocytes, the cytoplasm of which contains a considerable number of hypertrophied mitochondria, which accounts for their eosinophilia and swollen appearance.
How is a diagnosis of renal oncocytoma made?
Diagnosis Diagnosis. A diagnosis of renal oncocytoma is often suspected based on imaging studies such as computed tomography (CT scan) and/or magnetic resonance imaging (MRI scan). However, it can be difficult to differentiate a renal oncocytoma from renal cell carcinoma based on imaging studies alone.
Can a CT scan detect renal cell carcinoma?
Computed Tomography. A central hypoattenuating scar may be observed in 33% of cases, but this scar cannot be differentiated from the central necrosis commonly found in renal cell carcinoma (RCC). With the advent of multisection CT scanning, high-resolution thin sections through the kidneys may improve detection of the central scar.
Can a renal oncocytoma grow back after surgery?
These tumors are most often benign and metastasis is very rare. After renal oncocytomas are surgically removed, they typically don’t recur. The lifespan of affected people is usually not impacted by the tumor. [8] [1] [2]
Which is less attenuating renal parenchyma or oncocytoma?
Computed Tomography. On nonenhanced CT scans, oncocytomas appear isoattenuating or slightly hyperattenuating relative to the kidney parenchyma. On contrast-enhanced CT scans that are obtained during the nephrographic phase, the mass appears less attenuating than the renal parenchyma.
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