What is Clinolipid?

Clinolipid 20% Lipid Injectable Emulsion, USP for intravenous use is a proprietary 80% olive oil, 20% soybean oil emulsion that offers healthcare professionals a prescribing alternative to meet the diverse needs of adult patients requiring parenteral nutrition (PN).

Who makes Clinolipid?

FDA Approves Clinolipid (10/2013) Clinolipid (marketed by Baxter Healthcare, Illinois) contains a mixture of refined olive oil and refined soybean oil.

What are Intralipids used for?

Intralipid 10% (10% I.V. Fat Emulsion) is a source of calories and essential fatty acids used to provide calories to patients who are getting their nutrition through an injection into the vein. Intralipid 10% is also used to provide essential fatty acid to people who do not have enough of it.

What is the side effects of lipids?

What Are Side Effects of Clinolipid?

nausea and vomiting.
high levels of fat in the blood (hyperlipidemia)
high blood sugar (hyperglycemia)
low blood protein levels (hypoproteinemia)
urinary tract infection.
blood infection (septicemia)
fever.
yellowing of skin and eyes (jaundice)

How are injectable emulsions prepared?

This procedure is based on a spontaneous emulsification process, comprising the following steps: (1) dissolving the oil phase containing phospholipid in the alcoholic solution: (2) optionally dissolving the drug into the oily alcoholic phase and (3) mixing the product of step (2) with an aqueous preparation of …

When was Clinolipid FDA approved?

Oct 4, 2013
Development Timeline for Clinolipid

Date	Article
Oct 4, 2013	Approval FDA Approves Clinolipid for Intravenous Nutrition

How much do Intralipids cost?

The cost for Intralipid intravenous emulsion 20% is around $310 for a supply of 1000 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

How many calories are in a mL of SMOF lipids?

Intravenous lipid emulsions are a condensed source of energy and essential fatty acids, providing 9 kcal/g of energy. The caloric value of lipid emulsions varies with the lipid emulsion concentration. Lipid emulsions at 10%, 20%, and 30% concentrations yield 1.1 kcal/mL, 2 kcal/mL, and 3 kcal/mL, respectively.

How do you get rid of lipids?

The first ways to reduce your lipid levels are (1) eat less fat, (2) exercise regularly and (3) lose weight if you weigh too much. If you smoke, stop smoking. If these steps don’t lower your LDL level enough, your doctor may have you take medicine to take the fat out of your blood.

How long is Baxter clinolipid in refrigerated storage?

Clinolipid utilizes Baxter’s proprietary lipid blend, which has been used for more than 20 years outside the U.S. PN admixtures physically stable up to 9 days in refrigerated storage, followed by 48 hours at room temperature. 1 *

What kind of lipid is used in clinolipid?

Clinolipid utilizes Baxter’s proprietary lipid blend, which has been used for more than 20 years outside the United States and dosed over 100M times. 6 Clinolipid’s largest component is olive oil, which is rich in Omega-9 oleic acid. 2 Oleic acid is a monounsaturated fatty acid (MUFA) that is considered to be immune neutral.

When to use clinolipid 3 in 1 admixtures?

3 in 1 Admixtures with Clinolipid are stable for 9 days when refrigerated at 2-8 o C plus additional 48 hours at room temperature of 25 o C (+/-2 o C). 1 Use this aid to support introducing Clinolipid (Lipid Injectable Emulsion, USP), 20% for intravenous use into your PN program.