What is the mechanism of action for Docusate Sodium?
Mechanism of Action Docusate is an anionic surfactant (i.e., a surface-active agent). It lowers the surface tension at the oil-water interface of the feces, allowing water and lipids to penetrate the stool. This helps to hydrate and soften the fecal material, facilitating natural defecation.
What does Docusate Senna do?
DOCUSATE SODIUM; SENNA (doc CUE sayt SOE dee um; SEN na) contains a stool softener and a laxative. It is used to treat constipation.
What is the mechanism of action of Sennosides?
Senna contains sennosides which acts as a stimulant laxative. It works by irritating and stimulating intestinal cells, producing contractions in intestines, water influx to the intestines and bowel movement.
How is docusate sodium excreted?
Docusate sodium works by allowing more water to be absorbed by the stool. Docusate does not stay in the gastrointestinal tract, but is absorbed into the bloodstream and excreted via the gallbladder after undergoing extensive metabolism.
What is the action of Dulcolax?
Dulcolax (bisacodyl) is a laxative that stimulates bowel movements. Dulcolax is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure. Dulcolax tablets generally produce a bowel movement in 6 to 12 hours.
What are side effects of docusate senna?
Stomach/abdominal pain or cramping, nausea, diarrhea, or weakness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This medication may cause your urine to turn reddish-brown.
Which chemical is responsible for purgative action of Senna?
sennosides
Cassia senna Linn. (Caesalpineaceae) is an important medicinal plant, which has been widely used in Ayurveda. The active chemical components of the plant are anthraquinone glycosides – sennosides, especially sennosides A and B, which are responsible for the purgative action.
What is the difference between docusate sodium and Sennosides?
Sennosides are known as stimulant laxatives. They work by keeping water in the intestines, which helps to cause movement of the intestines. Docusate is known as a stool softener. It helps increase the amount of water in the stool, making it softer and easier to pass.
How do laxatives work Senna?
Senna works by stimulating the nerve endings in the walls of the large bowel (colon) and rectum. This makes the muscles in the bowel wall contract more often and with increased force, which moves the stools through the colon to the rectum so that the bowel can be emptied.
What is the purpose of a suppository?
Suppositories are another way to deliver drugs to the body when other routes, such as oral, cannot be used. A suppository is small and may be round, oval, or cone-shaped. A substance, such as cocoa butter or gelatin, surrounds the medication. The suppository dissolves to release the drug once inside the body.
What are the uses of Senna with docusate?
Docusate is a stool softener. It makes bowel movements softer and easier to pass. Senna is a laxative. It stimulates muscle movement in the intestines. The combination of docusate and senna is used to treat occasional constipation.
How many docusate sodium should I take?
The instructions for taking docusate sodium will be on the label of the pack. You can take up to five 100 mg-strength capsules over the course of a day, although you may not need this many. Take the capsules one at a time, at regular intervals throughout the day.
When are there side effects of docusate sodium?
Long Term Side Effects of Docusate Sodium (Colace): Stomach Ache: If you are taking Docusate Sodium (Colace) from the long time, you may go through stomach ache. Upset Stomach: Long term consumption of Docusate Sodium (Colace) can make your tummy upset. Diarrhea: Docusate Sodium (Colace) can make you feel bowel movements in your stomach.
Can I take docusate sodium and drink alcohol?
You can eat and drink normally while taking docusate sodium. It might be a good idea to stop eating pastries, puddings, sweets, cheese and cake for a while as these foods can make constipation worse. Can I drink alcohol with docusate sodium? Yes , you can drink alcohol with docusate sodium.