Which is a complication of vancomycin infusions?
During or soon after rapid infusion of vancomycin, patients may develop anaphylactoid reactions, including hypotension (see Animal Pharmacology), wheezing, dyspnea, urticaria, or pruritus. Rapid infusion may also cause flushing of the upper body (“red neck”) or pain and muscle spasm of the chest and back.
Why should vancomycin be administered slowly?
Slow intravenous administration of vancomycin should minimize the risk of infusion-related adverse effects.
What are the contraindications of vancomycin?
Who should not take VANCOMYCIN HCL?
- systemic mastocytosis.
- low levels of a type of white blood cell called neutrophils.
- hearing loss.
- kidney disease with likely reduction in kidney function.
What are the signs and symptoms of vancomycin toxicity?
Side Effects
- Black, tarry stools.
- blood in the urine or stools.
- continuing ringing or buzzing or other unexplained noise in the ears.
- cough or hoarseness.
- dizziness or lightheadedness.
- feeling of fullness in the ears.
- fever with or without chills.
- general feeling of tiredness or weakness.
What are contraindications of vancomycin?
What is the maximum rate of administration of vancomycin IV?
Vancomycin shall only be administered as slow intravenous infusion of at least one hour duration or at a maximum rate of 10 mg/min (whichever is longer) which is sufficiently diluted (at least 100 ml per 500 mg or at least 200 ml per 1000 mg) (see section 4.4).
Which is a possible infusion reaction if vancomycin is administered too quickly?
A possible side effect that may occur if vancomycin is infused too rapidly includes an allergic reaction (anaphylactoid reaction) known as “red man syndrome”. This is the most common allergic reaction in younger patients (under age 40) who received intravenous vancomycin.
What complications are associated with IV vancomycin treatment?
What is the adverse effect of vancomycin IV?
Vancomycin IV can also cause abnormal bleeding or bruising. It can also cause severe blistering on the skin, especially on the upper body including the arms and hands, as well as on the legs and feet. These side effects are rare, but life-threatening.
What are the dangers of vancomycin?
While this medication is very effective at treating this condition, its side effects can be very dangerous. Some of the most common side effects associated with vancomycin use include the development of an unusual taste in the mouth, stomach problems such as nausea and vomiting, allergic reactions, and even hearing or kidney damage.
What is the therapeutic effect of vancomycin?
Oral vancomycin is a glycopeptide antibiotic that is used for the treatment of Clostridium difficile diarrhea and staphylococcal enterocolitis. Vancomycin is a bactericidal antibiotic (it kills bacteria) that exerts its effects by preventing bacteria from forming cell walls, which they need to survive.
What are the signs of a vancomycin overdose?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity. Get emergency medical help if you have any of these signs of an allergic reaction to vancomycin: hives; difficult breathing; swelling of your face, lips, tongue, or throat .