Does thalassemia affect surgery?
Patients with thalassaemia may present for elective or emergency surgery 50, 51 such as therapeutic splenectomy, cholecystectomy due to bilirubin gallstone formation, correction of facial deformities and operative treatment of leg ulcers, fractures and extramedullary pseudotumours 52.
What are complications of beta thalassemia?
Beta thalassemia major causes major problems and can result in early death. Complications may include delayed growth, bone problems causing facial changes, liver and gall bladder problems, enlarged spleen, enlarged kidneys, diabetes, hypothyroidism, and heart problems.
Does thalassemia affect wound healing?
Major hemoglobinopathies such as thalassemia syndromes and sickle cell disorders (SCD) that are caused by genetic defects have been associated with chronic anemia and cuta- neous complications such as chronic leg ulcers. 1 These ulcers are typically difficult to heal due to the underlying cause of the ulceration.
Is thalassemia minor serious?
Thalassemia minor is a less serious form of the disorder. There are two main forms of thalassemia that are more serious. In alpha thalassemia, at least one of the alpha globin genes has a mutation or abnormality. In beta thalassemia, the beta globin genes are affected.
What is the common complications of treatment of thalassemia?
Complications are still common and include heart disease (heart failure and arrhythmias), chronic liver hepatitis, which can evolve in cirrhosis and, rarely, in hepatocellular carcinoma, endocrine problems (hypogonadism, hypothyroidism, diabetes, hypoparathyroidism), stunted growth, osteoporosis, thrombophilia and …
How is wound healing affected by diabetes?
People with uncontrolled diabetes may develop poor circulation. As circulation slows down, blood moves more slowly, which makes it more difficult for the body to deliver nutrients to wounds. As a result, the injuries heal slowly, or may not heal at all.
Is beta thalassemia minor life threatening?
If you have thalassemia, your outlook depends on the type of the disease. People who have mild or minor forms of thalassemia can typically lead normal lives. In severe cases, heart failure is a possibility. Other complications include liver disease, abnormal skeletal growth, and endocrine issues.
Does thalassemia make you high risk for Covid?
Having hemoglobin blood disorders like sickle cell disease (SCD) or thalassemia can make you more likely to get severely ill from COVID-19.
How is thalassemia treated?
People with severe thalassemia have a serious and life-threatening illness. They are treated with regular blood transfusions, iron chelation therapy, and bone marrow transplants.
What is a beta Thal trait?
Beta thal trait, sometimes called beta thalassemia minor, is a mild form of beta thalassemia. In beta thalassemia trait, there is enough beta globin for normal health. Your baby may have a slightly lower hemoglobin (anemia).
What is thalassemia trait?
Thalassemia Trait. Thalassemia is a genetic disease. This means that a person can only get thalassemia disease or trait by inheriting the genes for thalassemia from their parents. Genes determine what we look like, such as hair color, and are also responsible for many diseases.