How does dengue affect the eyes?
Eye complications due to Dengue: Subconjunctival haemorrhage, macular chorioretinitis, macular oedema, dengue related optic neuritis, retinal haemorrhage, vitritis, and anterior uveitis. Subconjunctival haemorrhage: The conjunctiva is a mucous membrane that covers the eye and the eyelids.
What is the pathophysiology of dengue?
Pathophysiology Primary manifestations of disease include capillary leak syndrome (plasma leakage due to DHF-specific endothelial cell dysfunction), thrombocytopenia (seen in all types of DENV infection, but extreme in DHF), hemorrhagic tendencies, and leukopenia.
What causes pain behind the eyes in dengue?
The exact mechanism of eye involvement in dengue viral infection is poorly understood. Multiple causes have been suspected and include viral factors, immune mediation, capillary leakage, stress, and hemorrhage. Eye involvement is classically seen at the lowest platelet count and when the count begins to rise.
Does eyes become red in dengue?
Pain in the muscles and joints – particularly in the legs. Pain behind the eyes – particularly when moving them. Nausea and vomiting. Red eyes.
What is the pattern of fever in dengue?
The fever pattern is classically biphasic or “saddleback,” breaking and then returning for 1 or 2 more days. In some people, the disease proceeds to a critical phase as the fever resolves. This phase is characterized by significant, diffuse leakage of plasma typically lasting 1–2 days.
Is dengue hemorrhagic fever?
Mild dengue fever causes a high fever and flu-like symptoms. The severe form of dengue fever, also called dengue hemorrhagic fever, can cause serious bleeding, a sudden drop in blood pressure (shock) and death.
What is dengue hemorrhagic?
Dengue hemorrhagic fever (DHF): A syndrome due to the dengue virus that tends to affect children under 10, causing abdominal pain, hemorrhage (bleeding) and circulatory collapse (shock).
Why does dengue cause hemorrhagic fever?
This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome. Severe dengue happens when your blood vessels become damaged and leaky. And the number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock, internal bleeding, organ failure and even death.
What is Choroiditis eye?
Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye. It is a form of posterior uveitis. If only the choroid is inflamed, not the retina, the condition is termed choroiditis.
Does eye pain in dengue?
The most common symptom of dengue is fever with any of the following: Nausea, vomiting. Rash. Aches and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain)
What are the patterns of fever?
There are five patterns: intermittent, remittent, continuous or sustained, hectic, and relapsing. With intermittent fever, the temperature is elevated but falls to normal (37.2°C or below) each day, while in a remittent fever the temperature falls each day but not to normal.
What are the signs and symptoms of dengue hemorrhagic fever?
DHF is characterized by sustained high fever for 2–7 days; bleeding diathesis such as positive tourniquet test, petechiae, epistaxis and hematemesis; thrombocytopenia with platelet counts ≤ 100 × 10 9 /L and plasma leakage due to increased vascular permeability evidenced by hemoconcentration, pleural effusion and ascites.
What is the pathophysiology and management of dengue?
Pathophysiology and management of dengue hemorrhagic fever. SUMMARY. Dengue infection is caused by any of four dengue virus serotypes. The clinical manifestations range from asymptomatic infection to undifferentiated fever, dengue fever and dengue hemorrhagic fever (DHF).
What are the hallmarks of dengue shock syndrome?
The major pathophysiologic hallmarks that distinguish DHF from DF and other diseases are increased vascular permeability leading to plasma leakage and circulatory collapse (Dengue Shock Syndrome/DSS).
What’s the difference between severe and mild dengue?
Since the recognition of DHF in the 1950s investigators have sought to define the clinical differences between severe and mild forms of dengue. Mild hemorrhagic manifestations, such as epistaxis, petechiae, gingival bleeding and menorrhagia, are accepted as part of the clinical picture of classic dengue.