What is the difference between thyroid storm and thyrotoxicosis?
Thyrotoxicosis is a common endocrine condition that may be secondary to a number of underlying processes. Thyroid storm (also known as thyroid or thyrotoxic crisis) represents the severe end of the spectrum of thyrotoxicosis and is characterized by compromised organ function.
What is the difference between hyperthyroidism and thyroid storm?
Symptoms of thyroid storm are similar to those of hyperthyroidism, but they are more sudden, severe, and extreme. This is why people with thyroid storm might not be able to seek care on their own. Common symptoms include: racing heart rate (tachycardia) that exceeds 140 beats per minute, and atrial fibrillation.
What clinical feature will differentiate thyrotoxicosis from thyroid crisis?
Hyperpyrexia (104–106°F) with diaphoresis is the key presenting feature. High fever induces profuse sweating and leads to insensible fluid losses, which is a differentiating feature between thyroid storm and thyrotoxicosis [1].
What is thyroid storm thyrotoxicosis?
Thyroid storm, also referred to as thyrotoxic crisis, is an acute, life-threatening, hypermetabolic state induced by excessive release of thyroid hormones (THs) in individuals with thyrotoxicosis. Thyroid storm may be the initial presentation of thyrotoxicosis in undiagnosed children, particularly in neonates.
What are the signs of a thyroid storm?
Symptoms of thyroid storm include:
- Feeling extremely irritable or grumpy.
- High systolic blood pressure, low diastolic blood pressure, and fast heartbeat.
- Nausea, vomiting, or diarrhea.
- High fever.
- Shock and delirium.
- Feeling confused.
- Feeling sleepy.
- Yellow skin or eyes.
What can trigger a thyroid storm?
Thyroid storm occurs due to a major stress such as trauma, heart attack, or infection in people with uncontrolled hyperthyroidism. In rare cases, thyroid storm can be caused by treatment of hyperthyroidism with radioactive iodine therapy for Graves disease.
What is autoimmune thyrotoxicosis?
GD is a systemic autoimmune thyroid disorder characterized by the infiltration of immune effector cells and thyroid-antigen-specific T cells into the thyroid and thyroid stimulating hormone receptor (TSHR) expressing tissues, i.e. orbit, skin, with the production of autoantibodies to well-defined thyroidal antigens.
What are the signs of thyroid storm?
What is the mortality risk from thyroid storm?
The mortality rate in people whose thyroid storm goes untreated is as high as 75 percent. When treated, mortality goes down to 20 percent to 30 percent. When thyroid storm does not respond to these approaches, plasmapheresis, a blood filtering treatment, is sometimes done to remove thyroid hormone from the bloodstream.
What are the possible causes of thyroid storm?
Causes. Thyroid storm occurs due to a major stress such as trauma, heart attack, or infection in people with uncontrolled hyperthyroidism . In rare cases, thyroid storm can be caused by treatment of hyperthyroidism with radioactive iodine therapy for Graves disease. This can occur even a week or more after the radioactive iodine treatment.
Signs and symptoms. Thyroid storm is characterized by an acute onset of symptoms of hyperthyroidism (fast heart rate, restlessness, agitation) accompanied by other features such as fever (temperatures often above 40 °C/104 °F), hypertension, mental status changes, diarrhea, and vomiting.
What is thyroid storm and its symptoms?
Thyroid storm is a crisis or life-threatening condition characterized by an exaggeration of the usual physiologic response seen in hyperthyroidism . Whereas hyperthyroidism can cause symptoms such as sweating, feeling hot, palpitations and weight loss – symptoms of thyroid storm are more severe, resulting in complications such as: fever. dehydration.