What does ASCUS with negative HPV mean?

What does ASCUS with negative HPV mean?

ASCUS (atypical squamous cells of undetermined significance) with negative HPV (human papilloma virus) test – because almost all cervical cancers and significant pre-cancers are caused by HPV, it is unlikely that the woman who is negative for HPV has a serious problem.

What causes ASCUS Pap smear with negative HPV?

The most common causes of ASCUS Pap smear results are noncancerous (benign) conditions, such as infections or inflammation. These conditions can cause cervical cells to appear abnormal. Eventually, however, most cells return to a normal appearance with time.

What percentage of ASCUS is cancer?

Without prompt treatment or close monitoring, about 0.25 percent of women with atypical squamous cells of undetermined significance (ASCUS) develop cervical cancer within two years.

Can ASCUS turn into cancer?

Thus women with ASCUS who are followed up regularly are at low risk for development of invasive cancer. Follow-up should depend on the relative risk in a woman with ASCUS to have or develop invasive cervical cancer.

When should I repeat Pap if ASCUS and negative HPV?

HPV testing (high risk types) is the preferred method for triage of ASCUS results using liquid cytology for ages 25-65. If 21-24 years, repeat PAP in 12 months. Screening practice should not change on the basis of HPV vaccination.

Should I be worried about ASCUS?

Since the progression from severe deterioration of cervical cells to cancer generally takes about 5 to 10 years, the condition does not pose any immediate threat, please do not worry excessively.

Is ASCUS Pap bad?

ASCUS paps are considered slightly abnormal results. According to the Association of Reproductive Health Professionals, normal, noncancerous cervical cells are present in about 75% of women with ASCUS results. In some cases, receiving an ASCUS pap can result from a poor sample.

Can ASCUS be bad?

Is ASC-US something to worry about?

Is ASC-US HPV high risk?

Atypical squamous cells of undetermined significance (ASCUS) cells, occurring in organized cytological screening, may be either high-risk human papillomavirus (HPV) positive or negative. To refine the assessment of women with ASCUS, a high-risk HPV-DNA test is recommended as triage in Sweden.

Can ASCUS be CIN3?

Cervical cytology is the standard of care for cervical cancer screening [1,2,3]. The 2-year cumulative risk of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer (CIN3+) within the ASCUS population was reported to be 8%–9% based on a single ASCUS interpretation in the ALTS [10].

What are the symptoms of ASCUS?

The ASCUS rate was higher in all parity groups and was commonly associated with pain in lower abdomen and vaginal discharge. The ASCUS rate was higher with erosion cervix, while the commonly associated sexually transmitted diseases (STD) were found to be Candida albicans (2.4%).