What is Rhenium 188 used for?
Rhenium-188-HEDP (188Re-HEDP) is a new and attractive radiopharmaceutical for the treatment of metastatic bone pain. As a product of 188W/188Re generator, it is convenient for clinical therapeutic use with a short physical half-life of 16.9 h and a maximal β-energy of 2.1 MeV.
What type of radiation does Rhenium 188 emit?
Rhenium-188 (188Re) is a high energy beta-emitting radioisotope with a short 16.9 h physical half-life, which has been shown to be a very attractive candidate for use in therapeutic nuclear medicine.
What type of emission is likely for re 188?
Re-188 decay is accompanied by a 155 keV predominant energy -emission, which could be detected by -cameras, for imaging, biodistribution, or absorbed radiation dose studies.
What element has a mass number of 188?
Properties of Osmium-188 Isotope:
| Properties of Osmium-188 Isotope: | OSMIUM-188 |
|---|---|
| Mass Number (A) | 188 |
| Nucleon Number (A) | 188 |
| Proton Number (Z) | 76 |
| Half-life | Stable |
What is the price of rhenium?
Rhenium metal pellet prices averaged $1,000 per kilogram in 2020, a 20% decrease from the annual average price in 2019.
Is radiopharmaceutical safe?
Radiopharmaceuticals are radioactive agents. However, when small amounts are used, the radiation your body receives from them is very low and is considered safe.
Who discovered rhenium 188?
Ida Noddack-Tacke
Discovery of rhenium and masurium (technetium) by Ida Noddack-Tacke and Walter Noddack. Forgotten heroes of nuclear medicine. Nuklearmedizin. 2015;54(6):N50-4.
How many neutrons does 188 W have?
List of isotopes
| Nuclide | Z | N |
|---|---|---|
| Excitation energy | ||
| 187W | 74 | 113 |
| 188W | 74 | 114 |
| 189W | 74 | 115 |
How many electrons does osmium-188?
Osmium-187 is composed of 76 protons, 111 neutrons, and 76 electrons. Osmium-188 is composed of 76 protons, 112 neutrons, and 76 electrons. Osmium-190 is composed of 76 protons, 114 neutrons, and 76 electrons.
How is rhenium used?
Uses: Used in filaments for mass spectrographs, thermistors, and catalysts and as an additive to tungsten- and molybdenum-based alloys. Rhenium wire is used in photoflash lamps. Rhenium is also used as an electrical contact material because it has good wear resistance and withstands arc corrosion.
What is the half life of rhenium 188?
Rhenium-188 (188 Re) is a high energy beta-emitting radioisotope with a short 16.9 h physical half-life, which has been shown to be a very attractive candidate for use in therapeutic nuclear medicine.
What can rhenium 188 re-labeled radiopharmaceuticals be used for?
The successful application of these 188 Re-labeled therapeutic radiopharmaceuticals has been reported in multiple early phase clinical trials for the management of various primary tumors, bone metastasis, rheumatoid arthritis, and endocoronary interventions.
Why is 188 re an important therapeutic radioisotope?
In addition, the low-abundant gamma emission of 155 keV (15%) is efficient for imaging and for dosimetric calculations. These key characteristics identify 188 Re as an important therapeutic radioisotope for routine clinical use.
Are there any radionuclides based on 188 re molecules?
Thus, preparation and targeting of 188 Re agents for therapy is similar to imaging agents prepared with 99m Tc, the most commonly used diagnostic radionuclide. Over the last three decades, radiopharmaceuticals based on 188 Re-labeled small molecules, including peptides, antibodies, Lipiodol and particulates have been reported.