What is fungal endophthalmitis?
Fungal endophthalmitis is a rare disease of ocular inflammation caused by fungal infections from either endogenous or exogenous sources. Because the clinical symptoms vary greatly and overlap with other ocular pathologies, fungal endophthalmitis presents as a diagnostic challenge.
What is the cause of endophthalmitis?
Endophthalmitis is the term used to describe severe inflammation of the tissues inside the eye. The inflammation is typically due to infection by bacteria (eg. Staphylococcus species, Streptococcus species, Gram-negative bacteria) or fungi (eg. Candida, Aspergillus).
What causes endogenous fungal endophthalmitis?
In the current study, endogenous endophthalmitis caused by molds, consisting mainly of Aspergillus species, was frequently associated with history of iatrogenic immunosuppression and organ transplantation.
How is fungal endophthalmitis treated?
Treatment of postcataract fungal endophthalmitis nearly always requires removal of the IOL in addition to an intraocular injection of an antifungal agent (either amphotericin or voriconazole), vitrectomy, and a systemic azole.
How is fungal endocarditis treated?
Current endocarditis guidelines recommend initial or induction therapy with AMB with or without flucytosine combined with surgical removal of vegetation, followed by chronic suppressive therapy with oral fluconazole.
Is endophthalmitis serious?
Endophthalmitis is infection inside the eye. It is a medical emergency. Eye surgery, eye injury, or infection in the bloodstream can cause the infection. Severe eye pain, eye redness, and loss of vision may occur.
What is the bacteria for endophthalmitis?
Common causes of endogenous bacterial endophthalmitis include S. aureus, B. cereus, and gram-negative organisms, including Escherichia coli, Neisseria meningitidis, and Klebsiella spp. (27, 81, 107, 142).