What is a UniProt accession?

What is a UniProt accession?

An accession number (AC) is assigned to each sequence upon inclusion into UniProtKB. Accession numbers are stable from release to release. If several UniProtKB entries are merged into one, for reasons of minimizing redundancy, the accession numbers of all relevant entries are kept.

Where is accession number in UniProt?

This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.

What is the UniProt code?

The mnemonic code ‘Y’ identifies the organism which is the biological source of the protein. It is generally composed of the first three letters of its genus name and the first two letters of its species name.

What is a UniProt identifier?

The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the proteome. It consists of the characters ‘UP’ followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome. UniProtKB entries can be linked to one or more UPIDs.

How do I retrieve data from UniProt?

Retrieving sequences from the website

  1. Perform your favorite query and view the resulting list of entries (e.g. this query retrieves all UniProtKB entries that are part of the human proteome: proteome:UP000005640)
  2. Click the Download button in the query result page.

What is UniProt database?

The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).

What is secondary accession number?

A unique accession number issued by INSD for each submitted sequence data is defined as the INSD accession number. In these cases, the new accession number is called the primary accession number, and the old accession number(s) is/are called the secondary accession number(s).

What kind of database is UniProt?

The UniProt Knowledgebase (UniProtKB) is an expertly curated database, a central access point for integrated protein information with cross-references to multiple sources. The UniProt Archive (UniParc) is a comprehensive sequence repository, reflecting the history of all protein sequences (1).

Is UniProt and Swiss Prot same?

UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProtKB/Swiss-Prot is a high quality manually annotated (reviewed) and non- redundant protein sequence database, which brings together experimental results and computed features.

Where is protein sequence in UniProt?

Are there more than one UniProtKB accession number?

UniProtKB accession numbers consist of 6 or 10 alphanumerical characters in the format: The three patterns can be combined into the following regular expression: Entries can have more than one accession number. This can be due to two distinct mechanisms: a) When two or more entries are merged, the accession numbers from all entries are kept.

How to retrieve a list of UniProt entries?

Select the Retrieve/ID mapping tab of the toolbar and enter or upload a list of identifiers (or gene names) to do one of the following: Retrieve the corresponding UniProt entries to download them or work with them on this website.

How to search for an IPR in UniProtKB?

For limited lists of such identifiers, it is possible to query UniProtKB using the text search form with identifiers combined by “or”, e.g. “interpro IPR014000” OR “interpro IPR014002” OR “interpro IPR014003”.

Do you need to download UniProtKB identifiers for go?

If you prefer to run your mapping locally, you can also download the data underlying this service. For performance reasons, databases where the mapping relationship to UniProtKB identifiers is one-to-many, e.g. GO, InterPro or PubMed, are not supported.

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