What is the contraindications of baclofen?
Although intrathecal use of baclofen is indicated in patients with spasticity of cerebral origin, oral baclofen is not recommended in patients with trauma-induced cerebral lesions, cerebral palsy, intracranial bleeding, parkinsonism, or a prior cerebrovascular accident (stroke).
What is a baclofen pump?
A baclofen pump is a little machine that is placed under the skin of one side of the abdomen (belly) near the hip bone. It is used to deliver baclofen directly into the spinal canal.
What should you know about the drug baclofen?
Baclofen relieves muscle spasm associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. 5. Tips Baclofen may be taken with or without food. Treatment should be started at a low dose and increased gradually as directed by your doctor.
When to use careful dose titration for baclofen?
-Careful dose titration is needed when spasticity is necessary to sustain upright posture and balance in locomotion or whenever spasticity is used to obtain optimal function. Allowing occasional spasms may help support circulatory function, possibly prevent the formation of deep vein thrombosis, and optimize activities of daily living.
How often should I take baclofen in a day?
-Initial dose: The following gradually increasing dosage regimen is suggested, but should be adjusted to suit individual patient requirements: 5 mg orally 3 times a day for 3 days, then 10 mg orally 3 times a day for 3 days, then 15 mg orally 3 times a day for 3 days, then 20 mg orally 3 times a day for 3 days.
When to double baclofen after a positive response?
INTRATHECAL POST-IMPLANT DOSE TITRATION PERIOD: -The screening dose that received a positive response should be doubled and administered over 24 hours, unless the efficacy of the bolus dose was maintained for more than 8 hours, in which case the starting daily dose should be the screening dose delivered over 24 hours.