What is erythema gyratum?

What is erythema gyratum?

Erythema gyratum repens (EGR) is a rare and characteristic, paraneoplastic rash associated with a variety of malignancies, most notably lung, esophageal, and breast cancers. This case report details the appearance, epidemiology, diagnosis, and treatment of EGR.

What causes erythema gyratum repens?

Erythema gyratum repens is associated with some nonneoplastic conditions, such as pulmonary tuberculosis, cryptogenic organizing pneumonia, lupus erythematosus, CREST (calcinosis, Raynaud phenomenon, esophageal motility disorder, sclerodactyly, and telangiectasia) syndrome, virginal breast hypertrophy, pityriasis rubra …

What is Figurate erythema?

Figurate erythema is a form of erythema that presents in a ring or an arc shape. An example is erythema marginatum.

How is erythema annulare Centrifugum treated?

Erythema annulare centrifugum (EAC) is usually self-limited. Topical steroids usually cause involution of the treated lesions, but they do not prevent the occurrence of new lesions or recurrence of the eruption. Systemic or injection steroid therapy is effective, but the eruption returns once these drugs are withdrawn.

What is erythema annulare?

Erythema annulare centrifugum (EAC) is a rare skin rash. The rash has small red bumps that spread out from a central area. The bumps often form a ring-like pattern, but may spread into irregular shapes. The center area may lighten up. You may have more than one area of rash.

What is eosinophilic annular erythema?

INTRODUCTION. Eosinophilic annular erythema (EAE) is an uncommon benign acute eosinophilic dermatosis of unknown etiology, originally described in children. 1,2. EAE is clinically characterized by recurrent annular, erythematous-edematous, pruritic lesions with a centrifugal growth pattern.

What is Necrolytic migratory erythema?

Necrolytic migratory erythema (NME) is a characteristic skin rash most often associated with the glucagonoma, an alpha-cell tumor of the pancreatic islets. It is usually seen as a part of the glucagonoma syndrome, a paraneoplastic syndrome which includes the triad of diabetes mellitus, NME, and weight loss.

What causes Figurate erythema?

The pathogenesis of erythema annulare centrifugum (EAC) is unknown, but it is probably due to a hypersensitivity reaction to a variety of agents, including drugs, arthropod bites, infections (bacterial, mycobacterial, viral, fungal, filarial), ingestion (blue cheese Penicillium), and malignancy.

How long does erythema annulare Centrifugum last?

The mean duration of erythema annulare centrifugum (EAC) is 11 months. However, the course has ranged from 4-6 weeks to 34 years (recurrent attacks). Most cases require no treatment and resolve spontaneously.

Is erythema annulare Centrifugum an autoimmune disease?

Erythema annulare centrifugum (EAC) is an unusual skin condition that appears as recurrent erythematous eruptions in the form of small and large annular plaques [1]. It is associated with various autoimmune disorders, infections, and few neoplastic conditions.

What kind of cancer is erythema gyratum repens associated with?

Background: Erythema gyratum repens is a rare, clinically specific, and distinctive paraneoplastic syndrome. It is associated with internal malignancy in 82% of patients. Objective: A 58-year-old man with erythema gyratum repens is described.

How long does it take for erythema gyratum repens to appear?

Most patients with erythema gyratum repens develop the eruption before the symptoms of tumor. The time interval between the eruption of erythema gyratum repens and the detection of the tumor can range from simultaneous presentation to up to 6 years after the rash.

What kind of erythema has a wood grain appearance?

Erythema gyratum repens is a rare paraneoplastic type of annular erythema with a distinctive figurate ‘wood-grain’ appearance. It has a strong association with malignancy. Erythema gyratum repens-like eruption* Erythema gyratum repens-like appearance in pemphigus foliaceus

How is the diagnosis of erythema annulare centrifugum confirmed?

The diagnosis can be confirmed by skin biopsy in which the typical features of superficial or deep erythema annulare centrifugum are noted: a dense perivascular lymphocytic infiltrate involving either the superficial or deep vascular plexus, which is known as a ‘coat-sleeve’ appearance.

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