Can I take niacin and aspirin together?
Aspirin — Taking aspirin before taking niacin may reduce flushing associated with this vitamin, but should only be done under your doctor’s supervision. Anticoagulants (blood thinners) — Niacin may make the effects of these medications stronger, increasing the risk of bleeding.
Can aspirin Reduce flushing?
Aspirin also significantly reduced intensity and duration of flushing (by 30-40%) compared with no aspirin. The two aspirin-containing treatments (i.e. pre- or concomitant treatment) were similar in their effects on flushing incidence, intensity and duration.
How do you counteract niacin flush?
Approximately 5% to 20% of patients discontinued treatment because of flushing. Flushing may be minimized by taking niacin with meals (or at bedtime with a low-fat snack), avoiding exacerbating factors (alcohol or hot beverages), and taking 325 mg of aspirin 30 minutes before niacin dosing.
Does ibuprofen help with niacin flush?
Taking aspirin or another nonsteroidal anti-inflammatory drug such as ibuprofen (Advil, Motrin) or naproxen (Aleve, Naprosyn) 30 minutes before niacin may reduce the flushing. If you take extended-release niacin at bedtime, the flushing will probably happen while you are asleep.
Why does aspirin help with niacin flushing?
Aspirin and related non-steroidal anti-inflammatory drugs (NSAIDs) can prevent the synthesis of prostaglandins by inhibiting both isoforms of COX (COX-1 and COX-2). The inhibition of COX also eliminates the flushing response to niacin (28,31–33).
Should you take aspirin before niacin?
The National Cholesterol Education Program recommends giving aspirin or another nonsteroidal anti-inflammatory drug before administering niacin.
What does niacin flushing feel like?
What is niacin flush? Niacin flush is a common side effect of taking high doses of niacin supplements. It’s uncomfortable, but it’s harmless. It appears as a flush of red on the skin, which may be accompanied by an itching or burning sensation ( 1 ).
How does aspirin reduce flushing with niacin?
How long does flushing from niacin last?
When niacin flush occurs, symptoms typically set in about 15–30 minutes after taking the supplement and taper off after about an hour. The symptoms mainly affect the face and upper body, and include ( 9 , 10 ): Reddening of the skin.
What happens to the body during a niacin flush?
A ‘Niacin flush’ is a side effect of taking high doses of supplemental niacin (Vitamin B3). The flush happens when niacin causes the small capillaries in your skin to dilate, which increases the flow of blood to the surface of the skin.
What causes niacin Flushing?
A niacin flush is a side effect of taking large doses of niacin (vitamin B3) supplements. The flush happens when the niacin causes the small blood vessels in your skin to dilate so more blood can rush through. Almost everyone who takes large doses of niacin experiences this flush.
Is it dangerous to take 500 mg of niacin daily?
But niacin (as nicotinic acid) in doses higher than 500 mg daily can cause severe side effects, including liver damage, diabetes, gastritis, and an elevation in blood levels of uric acid (which can cause gout). So researchers and nutrition experts developed inositol hexaniacinate.
What are the side effects of niacin?
Commonly reported side effects of niacin include: pruritus, nausea, and flushing. Other side effects include: skin rash, and vomiting.
What is flush niacin used for?
About Niacin Flush: Niacin is used to treat and prevent a lack of natural niacin in the body, and to lower cholesterol and triglycerides in the blood. It is also used to lower the risk of heart attack in people with high cholesterol who have already had a heart attack.