What is a median raphe cyst?

What is a median raphe cyst?

Median raphe cysts are cysts that develop on the median line in the male genital region in any area from the anus to the external meatus.[2] Median raphe cysts mostly present at birth and may remain asymptomatic or ignored during childhood. As the patient grows older, the cyst may also progress slowly.

What causes median raphe cyst?

Median raphe cysts are thought to arise from an abnormality in the formation of the urethra whereby embryonic nests persist during invagination and closure of the urogenital folds. Another theory holds they may form from ectopic Littre’s (periurethral) glands.

What is the median raphe?

The median raphe nucleus (MRN or MnR), also known as the nucleus raphes medianus (NRM) or superior central nucleus, is a brain region composed of polygonal, fusiform, and piriform neurons, which exists rostral to the nucleus raphes pontis.

Are there any cysts on the median raphe?

Median raphe cysts are rare congenital lesions along the male external genitalia. Until today, these cases were reported with different terms including mucoid cyst of the penile skin, genitoperineal cyst of the median raphe, parameatal cyst, hydrocystoma, and apocrine cystadenoma.

Where are cysts located on the male genitals?

Median raphe cysts (MRCs) are uncommon benign congenital lesions that can develop at any site along the midline of the ventral side of the male genital area, from the urethral meatus to the anus and the perineum (i.e.) along the median raphe of the male external genitalia [2].

Are there any cysts in the perianal region?

Perianal region is an extremely rare location for these lesions. Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o’clock in perianal region.

What makes up the epithelium of a cyst?

The epithelial lining of cyst consisted of keratinized and nonkeratinized stratified squamous epithelium (Figure 1 (b) ), pseudostratified ciliated epithelium (Figure 2 ), and scattered goblet cells (Figure 3 (a) ). Under the cyst epithelium, in some areas, hemosiderin laden macrophages, pigment of melanin, were seen.