What are the side effects of etomidate?
Common side effects of etomidate include:
- injection site pain,
- temporary muscle movements,
- fast or slow breathing,
- hiccups,
- snoring,
- high or low blood pressure,
- fast or slow heart rate,
- arrhythmias, and.
Why is etomidate not available in Australia?
CHOICE AND DOSES OF AGENTS etomidate is not available in Australia, and may be best avoided due to ongoing concerns: it causes adrenal suppression which may be linked to increased mortality in septic patients (though many argue that etomidate is safe)
How long does it take for etomidate to wear off?
Etomidate is rapidly metabolized in the liver. Minimal hypnotic plasma levels of unchanged drug are equal to or higher than 0.23 μg/mL; they decrease rapidly up to 30 minutes following injection and thereafter more slowly with a half-life value of about 75 minutes.
When should you not use etomidate?
Its use by infusion in trauma patients has been associated with an increase in mortality [16, 17] and has led to recommendations not to use etomidate in trauma patients [18].
What happens if you give too much etomidate?
Although uncommon, overdosage may occur from rapid or repeated injections. A decrease in blood pressure may follow rapid injection. No adverse cardiovascular or respiratory effects due to etomidate overdose have been reported.
Why do patients become hypotensive after intubation?
Hypotension after intubation is usually attributable to diminished central venous blood return to the heart secondary to elevated intrathoracic pressures.
What is the reversal agent for etomidate?
Calabadion 2 dose-dependently reverses the effects of ketamine and etomidate on electroencephalographic predictors of depth of anesthesia, as well as drug-induced hypotension, and shortens the time to recovery of righting reflex and functional mobility.
What happens if you push etomidate too fast?
Etomidate, when used in paralytic RSI, is pushed as rapidly as possible and is immediately followed by the neuromuscular blocking agent. This medication sequence renders the patient almost instantly unconscious and paralyzed.