What is oncocytoma caruncle?
The oncocytoma (oxyphil adenoma) is an uncommon tumor composed of transformed epithelial cells of the ducts of salivary glands and other organs. In two men, 66 and 75 years old, oncocytomas originated in the caruncle where they assumed rather characteristic features.
What is a caruncle lesion?
Lesions of the caruncle are uncommon. On account of the fact that the caruncle harbours skin elements, such as hair follicles, sebaceous glands, sweat glands, and accessory lacrimal tissue, the lesions developing from the caruncle are very diverse, making their clinical diagnosis very difficult.
What is a oncocytoma?
Renal oncocytoma is a benign (noncancerous) growth of the kidney. They generally do not cause any signs or symptoms and are often discovered incidentally (by chance) while a person is undergoing diagnostic imaging for other conditions.
What is a caruncle in anatomy?
Anatomical terminology The lacrimal caruncle, or caruncula lacrimalis, is the small, pink, globular nodule at the inner corner (the medial canthus) of the eye. It consists of tissue types of neighbouring eye structures. It may suffer from lesions and allergic inflammation.
What does it mean when your lacrimal Caruncle is swollen?
Lacrimal Gland swelling may be acute or chronic. Acute swelling is caused by a bacterial or viral infection such as mumps, Epstein-Barr virus, gonococcus and staphylococcus. Chronic swelling could be due to non-infectious inflammatory disorders such as thyroid eye disorder, sarcoidosis and orbital pseudotumor.
Can you have a cyst on your eyeball?
A conjunctival cyst is a cyst on the conjunctiva of your eye. The conjunctiva is that clear membrane that covers the white part of your eye. It also lines the inside of your eyelids.
What does a caruncle do?
The lacrimal caruncle is the small, pink, globular spot at the inner corner, or the medial canthus, of the eye. It contains both oil and sweat glands. The whitish material that sometimes accumulates in that region is from these glands. The tarsal plate is composed of connective tissue that gives support to the eyelids.
What causes a caruncle?
Caruncles are most common in post-menopausal women and in some cases pre-pubertal girls [6]. They are thought to arise due to reduced oestrogenisation of urethral smooth muscle leading to lack of support for the urethral mucosa. This urogenital atrophy allows the mucosa of the urethra to prolapse.
Should oncocytoma be removed?
Although many benign tumors do not require treatment unless they are causing unpleasant symptoms, it can be difficult to confidently differentiate a renal oncocytoma from renal cell carcinoma. Most affected people are, therefore, treated with surgery which allows for confirmation of the diagnosis.
Is an oncocytoma malignant?
Oncocytoma is a benign solid renal tumor. Unfortunately, it is usually difficult to distinguish an oncocytoma from an RCC on imaging, thus tissue sampling is usually required to make the diagnosis.
What is the function of the caruncle?
A caruncle is a fleshy outgrowth on a plant or animal. A caruncle’s function in a human eye is to moisturize the eye and protect it from bacteria. The reading mentions a “comb” because some birds have caruncles.
What causes a swollen caruncle?
The allergens ( i.e. pollen) irritates the caruncle and causing it to be inflammed and swollen. In addition, both the allergens and inflammatory “stuff” the eyes produces to fight the allergen accumulates in the caruncle area leading to become the epicenter of itchiness.
How often does oncocytoma of the caruncle occur?
Oncocytoma of the caruncle was first described in the literature in 1941. Oncocytomas are also seen in the thyroid, parathyroid, salivary glands, and kidneys. The incidence of ocular oncocytoma has been estimated to be 0.3 per million/year. Oncocytoma of the caruncle H&E 10x.
Are there any benign lesions on the caruncle?
Fifteen percent of the caruncular biopsies contained malignant or borderline malignant lesions, whereas the remaining 85% were benign entities. Most lesions present in the caruncle are benign. Although relatively rare, oncocytomas may be encountered by the dermatopathologist and may be confused for other neoplasms.
Are there any biopsies of the lacrimal caruncle?
Lesions of the lacrimal caruncle vary widely due to its unique composition. Rarely, dermatologists and dermatopathologists encounter biopsies taken from this location.
What kind of biomicroscopy is used for oncocytoma?
Fifteen of the oncocytoma cases underwent ultrasound biomicroscopy and anterior segment optical coherence tomography which showed mixed solid and cystic components without evidence of scleral invasion.