Is vinorelbine a Vesicant?
Vinorelbine, which is a moderate vesicant, also causes common irritation and burning sensations which are prevented by proper dilution, short infusion time and use of an adequately large vein[33].
What type of drug is vinorelbine?
Vinorelbine is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.
How do you administer vinorelbine?
Administer diluted NAVELBINE over 6 to 10 minutes into the side port of a free-flowing intravenous line followed by flushing with at least 75 to 125 mL of one of the solutions. NAVELBINE must only be administered intravenously.
What is the mechanism of action of vinorelbine?
Vinorelbine is a second-generation, semisynthetic vinca alkaloid. Its mechanism of action is through binding to microtubular proteins in the mitotic spindle, thereby preventing cell division during metaphase.
What is Navelbine used for?
Vinorelbine is a chemotherapy drug used to treat breast cancer. It’s also known by the brand name Navelbine.
How is Navelbine administered?
Administration Administer diluted NAVELBINE over 6 to 10 minutes into the side port of a free-flowing intravenous line followed by flushing with at least 75 to 125 mL of one of the solutions. NAVELBINE must only be administered intravenously.
Do you lose hair on vinorelbine?
When used on its own, vinorelbine may cause some mild, temporary hair thinning. Very rarely, it can cause complete hair loss.
Is vinorelbine a chemo drug?
Vinorelbine belongs to a class of chemotherapy drugs called plant alkaloids. Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea).
How do you reconstitute vinorelbine?
Syringe: The calculated dose of vinorelbine should be diluted to a concentration between 1.5 and 3.0 mg/mL and should be administered over 6 to 10 minutes into the side port of a free-flowing IV closest to the IV bag followed by flushing with at least 75 to 125 mL of one of the solutions.
What is the J code for vinorelbine?
J9390
2021 HCPCS Code J9390 : Injection, vinorelbine tartrate, 10 mg.
What is vinblastine made of?
Vinblastine is a chemical analogue of vincristine, an alkaloid derived from the Madagascar periwinkle plant Vinca rosea (Catharanthus roseus), from which it derives its name.
Is vinorelbine the same as Navelbine?