What causes low platelets in blood test?
Decreased production of platelets Some types of anemia. Viral infections, such as hepatitis C or HIV. Chemotherapy drugs and radiation therapy. Heavy alcohol consumption.
What causes elevated liver enzymes and low platelets?
Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is a condition that belongs to the hypertensive disorders of pregnancy, which include preeclampsia/eclampsia [4].
Does Gilbert’s syndrome cause low platelets?
with great interest. They investigated the effects of increased levels of bilirubin on the mean platelet volume (MPV) and other hematological parameters. They have found that MPV level was lower in the Gilbert’s syndrome patients than the normal population.
Why platelets are low in liver disease?
Thrombocytopenia, i.e., the reduction of platelet count in blood, is a common hematological complication of CLD caused by decreased production of hormone thrombopoietin (TPO) in the damaged liver and/or increased destruction of platelets through phagocytosis in the enlarged spleen, as well as the loss of hematopoietic …
Does fatty liver cause low platelets?
Patients with mild fatty liver had significantly (P = 0.042) lower platelet counts than those with moderate and severe fatty liver collectively (25.3 ± 0.2 × 104/µL vs. 26.1 ± 0.3 × 104/µL).
Does low platelets mean cirrhosis?
In fact, a low platelet count is used as a clinical diagnostic tool for the presence of cirrhosis and is included in the Aspartate Aminotransferase to Platelet Ratio Index and Fibrosis-4 scores, as well as in all of the noninvasive blood testing methods of diagnosing advanced liver disease.
What does it mean when your platelet count is low?
Thrombocytopenia is the medical term used to describe a low platelet count. Blood platelets are the tiny cells responsible for clotting the blood when you cut yourself.
What causes the body to not produce enough platelets?
Thrombocytopenia is a condition in which the body does not produce enough platelets because of disease or other conditions. Symptoms include internal and external bleeding. Treatment may involve treating the disease or condition that is causing the thrombocytopenia.
Can a low platelet count cause the spleen to swell?
The spleen is a small organ normally about the size of your fist. A number of conditions, including liver disease and some cancers, can cause your spleen to become enlarged. If for any reason your blood platelet count falls below normal, the condition is called thrombocytopenia.
How many platelets are in a microliter of blood?
Normally, you have anywhere from 150,000 to 450,000 platelets per microliter of circulating blood. Because each platelet lives only about 10 days, your body continually renews your platelet supply by producing new platelets in your bone marrow. Thrombocytopenia can be inherited or it may be caused by a number of medications or conditions.