How much water should I drink with cyclophosphamide?
Follow your doctor’s instructions carefully about how much fluid to drink every day. Some patients may have to drink up to 7 to 12 cups (3 quarts) of fluid a day. Usually it is best to take cyclophosphamide first thing in the morning, to reduce the risk of bladder problems.
What is the most common side effect of cyclophosphamide?
Nausea, vomiting, loss of appetite, stomach ache, diarrhea, or darkening of the skin/nails may occur. Nausea and vomiting can be severe. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting.
What should I monitor with cyclophosphamide?
Your doctor will order regular lab tests to check your response to cyclophosphamide and monitor for toxicity. Your blood counts – white blood cells, red blood cells and platelets – will be checked regularly. Your liver enzymes and urine will be checked regularly as well.
Does cyclophosphamide make you tired?
Tell your doctor immediately if any of these unlikely but serious side effects occur: pink/bloody urine, unusual decrease in the amount of urine, mouth sores, unusual tiredness or weakness, joint pain, easy bruising/bleeding, stopping of menstrual periods, existing wounds that are slow healing.
Can cyclophosphamide be liquid?
Cyclophosphamide is available as 50mg tablets. A liquid is available which contains cyclophosphamide 50mg/5ml.
Can cyclophosphamide be prepared as a liquid?
Cyclophosphamide (also called “cyclo”, Cytoxan®) is an anticancer medicine. It is given by mouth as a 25-mg and 50-mg capsule, or as a clear liquid. It also can be given as a clear liquid into a vein (IV).
Is cyclophosphamide a strong chemotherapy?
Cyclophosphamide is one of a number of medications first developed as a chemotherapy drug (a medication used in the treatment of cancer). It was discovered that — in addition to its usefulness in cancer — cyclophosphamide also has a significant ability to suppress the immune system.
How toxic is cyclophosphamide?
Clinically, damage to the bladder (haemorrhagic cystitis), immunosuppression (when not desired) and alopecia are the most significant toxicities associated with cyclophosphamide. Cardiotoxicity is also a possibility when very high doses are given.
Is cyclophosphamide a strong chemo drug?
Will I lose my hair on cyclophosphamide?
Hair loss: Temporary – usually begins 3-6 weeks after the start of therapy. Hair will grow back after treatment is completed although the color and/or texture may be different. Nausea and vomiting: more common with larger doses, usually beginning 6-10 hours after therapy.
How do you dilute cyclophosphamide?
If the solution is to be used for IV infusion, Cyclophosphamide (containing cyclophosphamide) is reconstituted by adding sterile water for injection or 0.9% sterile sodium chloride solution. Reconstituted Cyclophosphamide should be further diluted in 5% dextrose or 0.9% sodium chloride solution prior to infusion.
Should cyclophosphamide be stored in the fridge?
Liquid preparations of cyclophosphamide for oral administration may be prepared by dissolving cyclophosphamide for injection in Aromatic Elixir, National Formulary (NF) Such preparations should be stored under refrigeration in glass containers and used within 14 days.
What are the side effects of cyclophosphamide in men?
Infertility. Cyclophosphamide may cause infertility in both men and women who are treated with the medication. As with many of cyclophosphamide’s side–effects, the risk of infertility appears to be related to the length of time a patient receives the drug (and probably the cumulative dose, as well).
How is cyclophosphamide used in pediatric oncology?
It is used in pediatric oncology as part of the standard treatment for leukemia, solid tumors, and brain tumors. Cyclophosphamide is commonly administered intrave- nously but it is also available as an oral agent, although this is rarely used in children with cancer.
Are there any side effects to cyclophosphamide for vasculitis?
However, the doses of cyclophosphamide used to treat vasculitis are still high enough to cause a significant number of side–effects, and the drug must be used with great caution. In this section, we review the side–effects of cyclophosphamide.
Is there a link between cyclophosphamide and bladder cancer?
Cancer. Bladder cancer — Cyclophosphamide has a tendency to damage the bladder (see Bladder problems, below). This damage predisposes patients to the development of bladder cancer. The risk of bladder cancer (and of other bladder complications) is greater when cyclophosphamide is administered in the oral daily form.